Azizoglu DB, Perez K, Zheng SL, Rahman S, Rim EY, Anbarchian T, Fish M, Loh KM, Red-Horse K, Nusse R. Liver size is predetermined in the neonate by adding lobules at the periphery. In Revision, Nature. Submitted: 2023 Nov; 34 pages. bioRxiv 2023.10.12.562109

Synopsis: We find that the size of the adult mouse liver is predetermined in a neonatal period by the angiogenic capacity of a newly-identified endothelial progenitor pool, rather than by the proliferation rate of hepatocytes.

Azizoglu DB, Braitsch C, Marciano DK, Cleaver O. Afadin and RhoA control pancreatic endocrine mass via lumen morphogenesis. Genes Dev. 2017 Dec 1;31(23-24):2376-2390. (featured on journal cover)

Synopsis: We find that two cytoskeleton-linked molecules, Afadin and RhoA, support a 3-dimensional mesh of tubes in the embryonic pancreas that in turn serves as a niche for pancreatic progenitors and controls the final endocrine mass in this critical metabolic organ.

Azizoglu DB, Chong DC, Villasenor A, Magenheim J, Barry DM, Lee S, Marty-Santos L, Fu S, Dor Y, Cleaver O. Vascular development in the vertebrate pancreas. Dev Biol. 2016 Dec 1;420(1):67-78.

Synopsis: We provide a step-by-step anatomical and molecular characterization of how the pancreas is vascularized in the mouse embryo.