Azizoglu DB, Perez K, Zheng SL, Rahman S, Rim EY, Anbarchian T, Fish M, Loh KM, Red-Horse K, Nusse R. Liver size is predetermined in the neonate by adding lobules at the periphery. bioRxiv 2023.10.12.562109

Synopsis: We find that the size of the adult mouse liver is predetermined in a neonatal period by the angiogenic capacity of a newly-identified endothelial progenitor pool, rather than by the proliferation rate of hepatocytes.